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Photodynamic therapy for high-grade dysplasia of bile duct via a choledochoscope.
|Title||Photodynamic therapy for high-grade dysplasia of bile duct via a choledochoscope.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Zhou J-J, Xiong L, Li Q-L, Gu Y, Wen Y, Deng X-F, Miao X-Y|
|Journal||World journal of gastroenterology : WJG|
|Date Published||2013 Sep 7|
When a distal common bile duct neoplasm is at the stage of carcinoma in situ or high-grade dysplasia, it is difficult for the surgeon to decide whether to perform pancreaticoduodenectomy. Here we describe a patient with a progressive dysplastic lesion in the common bile duct, which developed from moderate-high to high-grade dysplasia in approximately 2 mo. The patient refused major surgery. Therefore, endoscopic-assisted photodynamic therapy was performed. The result at follow-up using a trans-T-tube choledochoscope showed that the lesion was completely necrotic. This report is the first to describe the successful treatment of high-grade dysplasia of the distal bile duct using photodynamic therapy via a choledochoscope.
|Alternate Journal||World J. Gastroenterol.|