Peripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction.

TitlePeripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction.
Publication TypeJournal Article
Year of Publication2013
AuthorsLi Q, Wang Y, Yu F, Wang YM, Zhang C, Hu C, Wu Z, Xu X, Hu S
JournalInternational journal of clinical and experimental pathology
Volume6
Issue6
Pagination1015-27
Date Published2013
Abstract

CD4(+)CD25(+) regulatory T (Treg) cells and Th17 cells play important roles in peripheral immunity. Oxidized low-density lipoprotein (ox-LDL) is an instrumental factor in atherogenesis. However, the changes of Th17/Treg cells in patients with acute cerebral Infarction (ACI) and impact on Th17/Treg by ox-LDL are not clear. Here, we examined the balance of Th17/Treg in ACI patients and the effect of ox-LDL on this balance.

DOI10.1016/j.fsi.2013.04.049
Alternate JournalInt J Clin Exp Pathol