Osteopontin knockdown suppresses non-small cell lung cancer cell invasion and metastasis.

TitleOsteopontin knockdown suppresses non-small cell lung cancer cell invasion and metastasis.
Publication TypeJournal Article
Year of Publication2013
AuthorsSun B-S, You J, Li Y, Zhang Z-F, Wang C-L
JournalChinese medical journal
Volume126
Issue9
Pagination1683-8
Date Published2013
Abstract

Osteopontin (OPN) was identified as one of the leading genes that promote the metastasis of malignant tumor. However, the mechanism by which OPN mediates metastasis in non-small cell lung cancer (NSCLC) remains unknown. The aim of the study is to investigate the biological significance and the related molecular mechanism of OPN expression in lung cancer cell line.

DOI10.4103/0974-2077.118423
Alternate JournalChin. Med. J.