One-step separation and purification of three lignans and one flavonol from Sinopodophyllum emodi by medium-pressure liquid chromatography and high-speed counter-current chromatography.

TitleOne-step separation and purification of three lignans and one flavonol from Sinopodophyllum emodi by medium-pressure liquid chromatography and high-speed counter-current chromatography.
Publication TypeJournal Article
Year of Publication2013
AuthorsWang P, Liu Y, Chen T, Xu W, You J, Liu Y, Li Y
JournalPhytochemical analysis : PCA
Volume24
Issue6
Pagination603-7
Date Published2013 Nov-Dec
Abstract

Lignans and flavonols are the primary constituents of Sinopodophyllum emodi and have been used as cathartic, anthelmintic, chemotherapeutic and anti-hypertensive compounds. Although these compounds have been isolated, there have been no reports on the separation of 4'-demethyl podophyllotoxin, podophyllotoxin, deoxypodophyllotoxin and kaempferol in one step by medium-pressure liquid chromatography (MPLC) and high-speed counter-current chromatography (HSCCC).

DOI10.1155/2013/195692
Alternate JournalPhytochem Anal