Nonviral gene targeting at rDNA locus of human mesenchymal stem cells.

TitleNonviral gene targeting at rDNA locus of human mesenchymal stem cells.
Publication TypeJournal Article
Year of Publication2013
AuthorsHu Y, Liu X, Long P, Xiao D, Cun J, Li Z, Xue J, Wu Y, Luo S, Wu L, Liang D
JournalBioMed research international
Volume2013
Pagination135189
Date Published2013
Abstract

Genetic modification, such as the addition of exogenous genes to the MSC genome, is crucial to their use as cellular vehicles. Due to the risks associated with viral vectors such as insertional mutagenesis, the safer nonviral vectors have drawn a great deal of attention.

DOI10.1371/journal.pone.0065940
Alternate JournalBiomed Res Int