Multiparametric magnetic resonance imaging analysis of the corticospinal tract in multiple sclerosis.

TitleMultiparametric magnetic resonance imaging analysis of the corticospinal tract in multiple sclerosis.
Publication TypeJournal Article
Year of Publication2007
AuthorsReich DS, Smith SA, Zackowski KM, Gordon-Lipkin EM, Jones CK, Farrell JAD, Mori S, van Zijl PCM, Calabresi PA
JournalNeuroImage
Volume38
Issue2
Pagination271-9
Date Published2007 Nov 1
Abstract

Muscle weakness is an important feature of multiple sclerosis and is responsible for much of the disability associated with that condition. Here, we describe the quantitative magnetic resonance imaging (MRI) attributes of the major intracerebral motor pathway--the corticospinal tract--in multiple sclerosis. To do so, we develop an intuitive method for creating and displaying spatially normalized tract-specific imaging data.

Alternate JournalNeuroimage