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MTA1 promotes the invasion and migration of non-small cell lung cancer cells by downregulating miR-125b.
|Title||MTA1 promotes the invasion and migration of non-small cell lung cancer cells by downregulating miR-125b.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Li Y, Chao Y, Fang Y, Wang J, Wang M, Zhang H, Ying M, Zhu X, Wang H|
|Journal||Journal of experimental & clinical cancer research : CR|
The metastasis-associated gene 1 (MTA1) has been identified as one critical regulator of tumor metastasis. Previously, we identified miR-125b as a downregualted miRNA in non-small cell lung cancer (NSCLC) cell line upon MTA1 depletion. However, the role of miR-125b and MTA1 in the regulation of NSCLC metastasis remains unclear.
|Alternate Journal||J. Exp. Clin. Cancer Res.|