MTA1 promotes the invasion and migration of non-small cell lung cancer cells by downregulating miR-125b.

TitleMTA1 promotes the invasion and migration of non-small cell lung cancer cells by downregulating miR-125b.
Publication TypeJournal Article
Year of Publication2013
AuthorsLi Y, Chao Y, Fang Y, Wang J, Wang M, Zhang H, Ying M, Zhu X, Wang H
JournalJournal of experimental & clinical cancer research : CR
Volume32
Pagination33
Date Published2013
Abstract

The metastasis-associated gene 1 (MTA1) has been identified as one critical regulator of tumor metastasis. Previously, we identified miR-125b as a downregualted miRNA in non-small cell lung cancer (NSCLC) cell line upon MTA1 depletion. However, the role of miR-125b and MTA1 in the regulation of NSCLC metastasis remains unclear.

DOI10.1177/1358863X13486312
Alternate JournalJ. Exp. Clin. Cancer Res.