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MRI biosensor for protein kinase A encoded by a single synthetic gene.
| Title | MRI biosensor for protein kinase A encoded by a single synthetic gene. |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Airan RD, Bar-Shir A, Liu G, Pelled G, McMahon MT, van Zijl PCM, Bulte JWM, Gilad AA |
| Journal | Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine |
| Volume | 68 |
| Issue | 6 |
| Pagination | 1919-23 |
| Date Published | 2012 Dec |
| Abstract | Protein kinases including protein kinase A (PKA) underlie myriad important signaling pathways. The ability to monitor kinase activity in vivo and in real-time with high spatial resolution in genetically specified cellular populations is a yet unmet need, crucial for understanding complex biological systems as well as for preclinical development and screening of novel therapeutics. |
| DOI | 10.1016/j.jviromet.2013.02.009 |
| Alternate Journal | Magn Reson Med |
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