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MRI biosensor for protein kinase A encoded by a single synthetic gene.
|Title||MRI biosensor for protein kinase A encoded by a single synthetic gene.|
|Publication Type||Journal Article|
|Year of Publication||2012|
|Authors||Airan RD, Bar-Shir A, Liu G, Pelled G, McMahon MT, van Zijl PCM, Bulte JWM, Gilad AA|
|Journal||Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine|
|Date Published||2012 Dec|
Protein kinases including protein kinase A (PKA) underlie myriad important signaling pathways. The ability to monitor kinase activity in vivo and in real-time with high spatial resolution in genetically specified cellular populations is a yet unmet need, crucial for understanding complex biological systems as well as for preclinical development and screening of novel therapeutics.
|Alternate Journal||Magn Reson Med|