Minor hypospadias: the "tip of the iceberg" of the partial androgen insensitivity syndrome.

TitleMinor hypospadias: the "tip of the iceberg" of the partial androgen insensitivity syndrome.
Publication TypeJournal Article
Year of Publication2013
AuthorsKalfa N, Philibert P, Werner R, Audran F, Bashamboo A, Lehors H, Haddad M, Guys JM, Reynaud R, Alessandrini P, Wagner K, Kurzenne JY, Bastiani F, Bréaud J, Valla JS, Lacombe GM, Orsini M, Daures J-P, Hiort O, Paris F, McElreavey K, Sultan C
JournalPloS one
Volume8
Issue4
Paginatione61824
Date Published2013
Abstract

Androgens are critical in male external genital development. Alterations in the androgen sensitivity pathway have been identified in severely undermasculinized boys, and mutations of the androgen receptor gene (AR) are usually found in partial or complete androgen insensitivity syndrome (AIS).

DOI10.1177/0300060513489800
Alternate JournalPLoS ONE