MicroRNA and piRNA profiles in normal human testis detected by next generation sequencing.

TitleMicroRNA and piRNA profiles in normal human testis detected by next generation sequencing.
Publication TypeJournal Article
Year of Publication2013
AuthorsYang Q, Hua J, Wang L, Xu B, Zhang H, Ye N, Zhang Z, Yu D, Cooke HJ, Zhang Y, Shi Q
JournalPloS one
Volume8
Issue6
Paginatione66809
Date Published2013
Abstract

MicroRNAs (miRNAs) are the class of small endogenous RNAs that play an important regulatory role in cells by negatively affecting gene expression at transcriptional and post-transcriptional levels. There have been extensive studies aiming to discover miRNAs and to analyze their functions in the cells from a variety of species. However, there are no published studies of miRNA profiles in human testis using next generation sequencing (NGS) technology.

DOI10.1371/journal.pone.0067679
Alternate JournalPLoS ONE