MicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer and is regulated by DNA methylation.

TitleMicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer and is regulated by DNA methylation.
Publication TypeJournal Article
Year of Publication2013
AuthorsLei H, Zou D, Li Z, Luo M, Dong L, Wang B, Yin H, Ma Y, Liu C, Wang F, Zhang J, Yu J, Li Y
JournalPloS one
Volume8
Issue4
Paginatione60369
Date Published2013
Abstract

Gastric cancer is the most frequent gastrointestinal tumor in adults and is the most lethal form of human cancer. Despite of the improvements in treatments, the underlying mechanism of gastric carcinogenesis is not well known. To define novel modulators that regulate susceptibility to tumorgenesis, we focused on miR-219-2-3p.

DOI10.1177/0300060513489800
Alternate JournalPLoS ONE