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Mammographic density and breast cancer: a comparison of related and unrelated controls in the Breast Cancer Family Registry.
|Title||Mammographic density and breast cancer: a comparison of related and unrelated controls in the Breast Cancer Family Registry.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Linton L, Martin LJ, Li Q, Huszti E, Minkin S, John EM, Rommens J, Paterson AD, Boyd NF|
|Journal||Breast cancer research : BCR|
|Date Published||2013 May 25|
Percent mammographic density (PMD) is a strong and highly heritable risk factor for breast cancer. Studies of the role of PMD in familial breast cancer may require controls, such as the sisters of cases, selected from the same 'risk set' as the cases. The use of sister controls would allow control for factors that have been shown to influence risk of breast cancer such as race/ethnicity, socioeconomic status and a family history of breast cancer, but may introduce 'overmatching' and attenuate case-control differences in PMD.
|Alternate Journal||Breast Cancer Res.|