Magnetic resonance microscopy of mouse brain development.

TitleMagnetic resonance microscopy of mouse brain development.
Publication TypeJournal Article
Year of Publication2006
AuthorsMori S, Zhang J, Bulte JWM
JournalMethods in molecular medicine
Volume124
Pagination129-47
Date Published2006
Abstract

Magnetic resonance imaging (MRI) is increasingly becoming an important tool to study anatomy of rodent brains. Compared with histology, it has clear advantages because the entire 3D object can be captured as an image nondestructively. However, low imaging resolution and a small number of available contrast mechanisms are two critical disadvantages. In this article, the future potential of magnetic resonance (MR) microimaging is discussed, with special emphasis on diffusion tensor microimaging as an effective contrast mechanism for the developing central nervous system.

Alternate JournalMethods Mol. Med.