Impaired lipopolysaccharide responsiveness of cord blood mononuclear cells and the risk of asthma: a longitudinal study.

TitleImpaired lipopolysaccharide responsiveness of cord blood mononuclear cells and the risk of asthma: a longitudinal study.
Publication TypeJournal Article
Year of Publication2013
AuthorsGoldberg MR, Elizur A, Luknar-Gabor N, Koch P, Tovbin J, Katz Y
JournalPediatric research
Volume74
Issue2
Pagination211-6
Date Published2013 Aug
Abstract

We previously demonstrated that the proliferative response to lipopolysaccharide (LPS) in cord blood mononuclear cells (CBMCs) is negatively correlated with the induced expression of interleukin (IL)-4. Our aim, therefore, was to examine whether an impaired cellular response to LPS in infancy is associated with the risk for asthma.

DOI10.1186/2090-5009-9-1
Alternate JournalPediatr. Res.