Impact of family history of cancer on the incidence of mutation in epidermal growth factor receptor gene in non-small cell lung cancer patients.

TitleImpact of family history of cancer on the incidence of mutation in epidermal growth factor receptor gene in non-small cell lung cancer patients.
Publication TypeJournal Article
Year of Publication2013
AuthorsHe Y, Li S, Ren S, Cai W, Li X, Zhao C, Li J, Chen X, Gao G, Li W, Zhou F, Zhou C
JournalLung cancer (Amsterdam, Netherlands)
Volume81
Issue2
Pagination162-6
Date Published2013 Aug
Abstract

Epidermal growth factor receptor (EGFR) activating mutation is an important predictive biomarker of EGFR tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC), while family history of cancer also plays an important role in the neoplasia of lung cancer. This study aimed to investigate the association between family history of cancer and EGFR mutation status in NSCLC population.

DOI10.1155/2013/748435
Alternate JournalLung Cancer