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Hybrid assemblies based on a gadolinium-containing polyoxometalate and a cationic polymer with spermine side chains for enhanced MRI contrast agents.
|Title||Hybrid assemblies based on a gadolinium-containing polyoxometalate and a cationic polymer with spermine side chains for enhanced MRI contrast agents.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Chai W, Wang S, Zhao H, Liu G, Fischer K, Li H, Wu L, Schmidt M|
|Journal||Chemistry (Weinheim an der Bergstrasse, Germany)|
|Date Published||2013 Sep 27|
Supramolecular assembly: Spherical and stable hybrid assemblies based on a cationic polymer with spermine side chains and an anionic Gd(3+)-containing polyoxometalate cluster (GdW) are prepared by electrostatic interaction. The T1-weighted MRI performance of GdW is enhanced about three times in the assemblies; meanwhile, the assemblies show good biocompatibility, which enables them to be promising candidates for MRI contrast agents.