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Hawley H. Seiler Resident Award. Transcriptional profile of brain injury in hypothermic circulatory arrest and cardiopulmonary bypass.
|Title||Hawley H. Seiler Resident Award. Transcriptional profile of brain injury in hypothermic circulatory arrest and cardiopulmonary bypass.|
|Publication Type||Journal Article|
|Year of Publication||2010|
|Authors||Allen JG, Weiss ES, Wilson MA, Arnaoutakis GJ, Blue ME, Talbot CC, Jie C, Lange MS, Troncoso JC, Johnston MV, Baumgartner WA|
|Journal||The Annals of thoracic surgery|
|Date Published||2010 Jun|
Little is known about the molecular mechanisms of neurologic complications after hypothermic circulatory arrest (HCA) with cardiopulmonary bypass (CPB). Canine genome sequencing allows profiling of genomic changes after HCA and CPB alone. We hypothesize that gene regulation will increase with increased severity of injury.
|Alternate Journal||Ann. Thorac. Surg.|