Gestational zinc deficiency impairs humoral and cellular immune responses to hepatitis B vaccination in offspring mice.

TitleGestational zinc deficiency impairs humoral and cellular immune responses to hepatitis B vaccination in offspring mice.
Publication TypeJournal Article
Year of Publication2013
AuthorsZhao N, Wang X, Zhang Y, Gu Q, Huang F, Zheng W, Li Z
JournalPloS one
Volume8
Issue9
Paginatione73461
Date Published2013
Abstract

Gestational zinc deficiency has been confirmed to impair the infant immune function. However, knowledge about effects of maternal mild zinc deficiency during pregnancy on hepatitis B vaccine responsiveness in offspring is limited. In this report, we aimed to examine how maternal zinc deficiency during pregnancy influences humoral and cellular immune responses to hepatitis B vaccination in offspring of BALB/c mice.

DOI10.1007/s12011-013-9822-5
Alternate JournalPLoS ONE