Genetic variations in TERT-CLPTM1L genes and risk of lung cancer in Chinese women nonsmokers.

TitleGenetic variations in TERT-CLPTM1L genes and risk of lung cancer in Chinese women nonsmokers.
Publication TypeJournal Article
Year of Publication2013
AuthorsLi C, Yin Z, Wu W, Li X, Ren Y, Zhou B
JournalPloS one
Volume8
Issue5
Paginatione64988
Date Published2013
Abstract

The TERT gene is the reverse transcriptase component of telomerase and is essential for the maintenance of telomere DNA length, chromosomal stability and cellular immortality. CLPTM1L gene encodes a protein linked to cisplatin resistance, and it is well conserved and express in various normal or malignant tissues, including lung.

DOI10.1155/2013/589474
Alternate JournalPLoS ONE