News & Updates
Search Research Content
Resource Finder at Kennedy Krieger Institute
A free resource that provides access to information and support for individuals and families living with developmental disabilities.
A functional link between FOXA1 and breast cancer SNPs.
|Title||A functional link between FOXA1 and breast cancer SNPs.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Katika MR, Hurtado A|
|Journal||Breast cancer research : BCR|
|Date Published||2013 Feb 18|
ABSTRACT: Genome-wide association studies have revealed a multitude of breast cancer-associated SNPs. The majority of these SNPs are located in noncoding regions of the genome. Yet how they contribute to breast cancer development is unknown. Recently, a groundbreaking study by the Lupien group has shown that risk-associated SNPs of breast cancer are enriched for FOXA1 binding sites, which influences the function of this transcription factor.
|Alternate Journal||Breast Cancer Res.|