News & Updates
Search Research Content
Resource Finder at Kennedy Krieger Institute
A free resource that provides access to information and support for individuals and families living with developmental disabilities.
A functional common polymorphism of the ABCB1 gene is associated with chronic kidney disease and hypertension in Chinese.
|Title||A functional common polymorphism of the ABCB1 gene is associated with chronic kidney disease and hypertension in Chinese.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Liu M, Li Y, Citterio L, Huang Q-F, Zeng W-F, Sheng C-S, Wei F-F, Dong Q, Li G-L, Kang Y-Y, Zhang L, Xu T-Y, Li J-J, Song J, Manunta P, Wang J-G|
|Journal||American journal of hypertension|
|Date Published||2013 Dec|
Permeability glycoprotein is encoded by the ATP-binding cassette B1 gene (ABCB1) and is an extruder of toxic metabolites in the kidney. A functional common polymorphism (C3435T, rs1045642) in the human ABCB1 gene has been found to be associated with allograft outcome in kidney transplant patients. In this study, we investigated the association of the C3435T polymorphism with renal function and blood pressure (BP) in 2 Chinese populations.
|Alternate Journal||Am. J. Hypertens.|