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FFAS-3D: improving fold recognition by including optimized structural features and template re-ranking.
|Title||FFAS-3D: improving fold recognition by including optimized structural features and template re-ranking.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Xu D, Jaroszewski L, Li Z, Godzik A|
|Journal||Bioinformatics (Oxford, England)|
|Date Published||2013 Nov 11|
Homology detection enables grouping proteins into families and prediction of their structure and function. The range of application of homology-based predictions can be significantly extended by using sequence profiles and incorporation of local structural features. However, incorporation of the latter terms varies a lot between existing methods, and together with many examples of distant relations not recognized even by the best methods, suggests that further improvements are still possible.