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Facile synthesis of tetrasaccharide aided by fluorous chemistry toward a dengue virus vaccine.
|Title||Facile synthesis of tetrasaccharide aided by fluorous chemistry toward a dengue virus vaccine.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Zhang Y, Liu B, Liu G|
|Date Published||2013 Aug|
We report the synthesis of a tetrasaccharide with side chain using a light-fluorous-tagged glycosyl donor through the double glycosylation and gradient fluorous solid-phase extraction by adding a little of DCM to improve the solubility for retention for the first time. This convergent method has high efficacy by saving much time and solvent.
|Alternate Journal||Mol. Divers.|