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Fabrication of red-blood-cell-like polyelectrolyte microcapsules and their deformation and recovery behavior through a microcapillary.
|Title||Fabrication of red-blood-cell-like polyelectrolyte microcapsules and their deformation and recovery behavior through a microcapillary.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||She S, Li Q, Shan B, Tong W, Gao C|
|Journal||Advanced materials (Deerfield Beach, Fla.)|
|Date Published||2013 Oct 25|
Multilayer microcapsules with a biconcave discoidal shape mimicking red blood cells (RBCs) are fabricated. The structure of the RBC-like microcapsules is verified by scanning electron and confocal laser scanning microscopies. The capsules show elastic deformation after being forced through a microcapillary with a smaller diameter, exhibiting a high recovery ratio of ≈90%. When the capsules are coated with hemoglobin (Hb),they are able to reversibly bind and release oxygen.
|Alternate Journal||Adv. Mater. Weinheim|