Exploring the role of human miRNAs in virus-host interactions using systematic overlap analysis.

TitleExploring the role of human miRNAs in virus-host interactions using systematic overlap analysis.
Publication TypeJournal Article
Year of Publication2013
AuthorsLi Z, Cui X, Li F, Li P, Ni M, Wang S, Bo X
JournalBioinformatics (Oxford, England)
Volume29
Issue19
Pagination2375-9
Date Published2013 Oct 1
Abstract

Human miRNAs have recently been found to have important roles in viral replication. Understanding the patterns and details of human miRNA interactions during virus-host interactions may help uncover novel antiviral therapies. Based on the abundance of knowledge available regarding protein-protein interactions (PPI), virus-host protein interactions, experimentally validated human miRNA-target pairs and transcriptional regulation of human miRNAs, it is possible to explore the complex regulatory network that exists between viral proteins and human miRNAs at the system level.

DOI10.2147/NDT.S47099
Alternate JournalBioinformatics