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Exploring the role of human miRNAs in virus-host interactions using systematic overlap analysis.
|Title||Exploring the role of human miRNAs in virus-host interactions using systematic overlap analysis.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Li Z, Cui X, Li F, Li P, Ni M, Wang S, Bo X|
|Journal||Bioinformatics (Oxford, England)|
|Date Published||2013 Oct 1|
Human miRNAs have recently been found to have important roles in viral replication. Understanding the patterns and details of human miRNA interactions during virus-host interactions may help uncover novel antiviral therapies. Based on the abundance of knowledge available regarding protein-protein interactions (PPI), virus-host protein interactions, experimentally validated human miRNA-target pairs and transcriptional regulation of human miRNAs, it is possible to explore the complex regulatory network that exists between viral proteins and human miRNAs at the system level.