Exploration of macro-micro biomarkers for dampness-heat syndrome differentiation in different diseases.

TitleExploration of macro-micro biomarkers for dampness-heat syndrome differentiation in different diseases.
Publication TypeJournal Article
Year of Publication2013
AuthorsDai J, Sun S, Peng J, Cao H, Zheng N, Fang J, Li Q, Jiang J, Zhang Y, Hu Y
JournalEvidence-based complementary and alternative medicine : eCAM
Volume2013
Pagination706762
Date Published2013
Abstract

Increased attention is being paid to traditional Chinese medicine (TCM) as a complementary and alternative medicine to provide an effective approach for personalized diagnosis and clinical treatment. TMC performs treatment based on differentiation of TCM syndrome (ZHENG), which may identify special phenotypes by symptoms and signs of patients even if they are in different diseases. There has, however, been skepticism and criticism because syndrome classification only depends on observation, knowledge, and clinical experience of TCM practitioners, which lacks objectivity and repeatability. In order to transform syndrome classification into mainstream medicine, we introduce a macro-micro approach that combines symptoms, clinical indicators, and metabolites. The present paper explores the macro-micro biomarkers of dampness-heat syndrome in chronic hepatitis B and nonalcoholic fatty liver patients, which could provide the basis for developing a possible population-screening tool for selecting target individuals and creating an evaluation index for personalized treatment.

DOI10.1155/2013/101805
Alternate JournalEvid Based Complement Alternat Med