Evaluation of capecitabine and oxaliplatin administered prior to and then concomitant to radiotherapy in high risk locally advanced rectal cancer.

TitleEvaluation of capecitabine and oxaliplatin administered prior to and then concomitant to radiotherapy in high risk locally advanced rectal cancer.
Publication TypeJournal Article
Year of Publication2013
AuthorsGao Y-H, An X, Sun W-J, Cai J, Cai M-Y, Kong L-H, Lin J-Z, Liu G-C, Tang J-H, Wu X-J, Chen G, Pan Z-Z, Ding P-R
JournalJournal of surgical oncology
Date Published2013 Nov 28
Abstract

Systemic failure remains a predominant issue in locally advanced rectal cancer (LARC). A new strategy using capecitabine and oxaliplatin (XELOX regimen) administered prior to and then concomitant to radiotherapy for high risk LARC is developed in our practice. The aim of the present study was to evaluate the short-term efficacy and toxicities of this strategy.

DOI10.1073/pnas.1317807110
Alternate JournalJ Surg Oncol