Enhancement of sensitivity of paper-based sensor array for the identification of heavy-metal ions.

TitleEnhancement of sensitivity of paper-based sensor array for the identification of heavy-metal ions.
Publication TypeJournal Article
Year of Publication2013
AuthorsFeng L, Li X, Li H, Yang W, Chen L, Guan Y
JournalAnalytica chimica acta
Volume780
Pagination74-80
Date Published2013 May 30
Abstract

Paper-based microfluidic devices have been widely investigated in recent years. Among various detection techniques, colorimetric method plays a very important role in paper-based microfluidic devices. The limitation, however, is also clear: they generally require highly sensitive indicators. In this work, we have developed a novel enrichment-based paper test for the discrimination of heavy-metal ions. Comparing to regular paper-based microfluidic devices, enrichment-based technique showed largely improved sensitivity. Combining with eight pyridylazo compounds and array technologies-based pattern-recognition, we have obtained the discrimination capability of eight different heavy-metal ions at same concentration as low as 50 μM using our enrichment-based pyridylazo compounds array paper. Identification of the heavy-metal ions was readily achieved using a standard chemometric approach. This method can be, of course, used for other analytes as well.

DOI10.3978/j.issn.2225-319X.2013.07.23
Alternate JournalAnal. Chim. Acta