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Elevated arteriolar cerebral blood volume in prodromal Huntington's disease.
|Title||Elevated arteriolar cerebral blood volume in prodromal Huntington's disease.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Hua J, Unschuld PG, Margolis RL, van Zijl PCM, Ross CA|
|Journal||Movement disorders : official journal of the Movement Disorder Society|
|Date Published||2013 Jul 11|
Neurovascular alterations have been implicated in the pathophysiology of Huntington's disease (HD). Because arterioles are most responsive to metabolic alterations, arteriolar cerebral blood volume (CBVa ) is an important indicator of cerebrovascular regulation. The objective of this pilot study was to investigate potential neurovascular (CBVa ) abnormality in prodromal-HD patients and compare it with the widely used imaging marker: brain atrophy.
|Alternate Journal||Mov. Disord.|