Effects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis.

TitleEffects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis.
Publication TypeJournal Article
Year of Publication2013
AuthorsZhu XX, Yang L, Li YJ, Zhang D, Chen Y, Kostecká P, Kmoníčková E, Zídek Z
JournalPharmacological reports : PR
Volume65
Issue2
Pagination410-20
Date Published2013
Abstract

In addition to recognized antimalarial effects, Artemisia annua L. (Qinghao) possesses anticancer properties. The underlying mechanisms of this activity are unknown. The aim of our experiments was to investigate the effects of distinct types of compounds isolated from A. annua on the immune-activated production of major mediators of angiogenesis playing a crucial role in growth of tumors and formation of metastasis.

DOI10.1155/2013/813450
Alternate JournalPharmacol Rep