Effective noninvasive zygosity determination by maternal plasma target region sequencing.

TitleEffective noninvasive zygosity determination by maternal plasma target region sequencing.
Publication TypeJournal Article
Year of Publication2013
AuthorsZheng J, Xu C, Guo J, Wei Y, Ge H, Li X, Zhang C, Jiang H, Pan L, Tang W, Xie W, Zhang H, Zhao Y, Jiang F, Chen S, Wang W, Xu X, Chen F, Huang H, Jiang H
JournalPloS one
Volume8
Issue6
Paginatione65050
Date Published2013
Abstract

Currently very few noninvasive molecular genetic approaches are available to determine zygosity for twin pregnancies in clinical laboratories. This study aimed to develop a novel method to determine zygosity by using maternal plasma target region sequencing.

DOI10.1371/journal.pone.0065940
Alternate JournalPLoS ONE