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Early characteristics of Sturge-Weber syndrome shown by perfusion MR imaging and proton MR spectroscopic imaging.
|Title||Early characteristics of Sturge-Weber syndrome shown by perfusion MR imaging and proton MR spectroscopic imaging.|
|Publication Type||Journal Article|
|Year of Publication||2003|
|Authors||Lin DDM, Barker PB, Kraut MA, Comi A|
|Journal||AJNR. American journal of neuroradiology|
|Date Published||2003 Oct|
We report the case of a 9-month-old boy with Sturge-Weber syndrome and new onset of seizure. Perfusion MR imaging showed early changes compatible with impaired venous drainage in the affected hemisphere, whereas proton MR spectroscopic imaging revealed a focal parietal area of elevated choline without significant alteration of N-acetylaspartate levels. The perfusion and subtle metabolic abnormalities are comparable with the extent of the overlying leptomeningeal enhancement, illustrating the early pathophysiological manifestation of this disease.
|Alternate Journal||AJNR Am J Neuroradiol|