Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia.

TitleDual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia.
Publication TypeJournal Article
Year of Publication2008
AuthorsWalczak P, Zhang J, Gilad AA, Kedziorek DA, Ruiz-Cabello J, Young RG, Pittenger MF, van Zijl PCM, Huang J, Bulte JWM
JournalStroke; a journal of cerebral circulation
Volume39
Issue5
Pagination1569-74
Date Published2008 May
Abstract

In animal models of stroke, functional improvement has been obtained after stem cell transplantation. Successful therapy depends largely on achieving a robust and targeted cell engraftment, with intraarterial (IA) injection being a potentially attractive route of administration. We assessed the suitability of laser Doppler flow (LDF) signal measurements and magnetic resonance (MR) imaging for noninvasive dual monitoring of targeted IA cell delivery.

DOI10.1203/PDR.0b013e318174e70e
Alternate JournalStroke