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A dual DTI approach to analyzing white matter in children with dyslexia.
|Title||A dual DTI approach to analyzing white matter in children with dyslexia.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Carter JC, Lanham DC, Cutting LE, Clements-Stephens AM, Chen X, Hadzipasic M, Kim J, Denckla MB, Kaufmann WE|
|Date Published||2009 Jun 30|
Using voxel-based (VBA) and region-of-interest (ROI) diffusion tensor imaging (DTI) analyses, we examined white matter (WM) organization in seven children with dyslexia and six age-matched controls. Both methods demonstrated reduced fractional anisotropy (FA) in the left superior longitudinal fasciculus (SLF) and abnormal orientation in the right SLF in dyslexics. Application of this complementary dual DTI approach to dyslexia, which included novel analyses of fiber orientation, demonstrates its usefulness for analyzing mild and complex WM abnormalities.
|Alternate Journal||Psychiatry Res|