Diffusion tensor imaging of the optic nerve in multiple sclerosis: association with retinal damage and visual disability.

TitleDiffusion tensor imaging of the optic nerve in multiple sclerosis: association with retinal damage and visual disability.
Publication TypeJournal Article
Year of Publication2011
AuthorsSmith SA, Williams ZR, Ratchford JN, Newsome SD, Farrell SK, Farrell JAD, Gifford A, Miller NR, van Zijl PCM, Calabresi PA, Reich DS
JournalAJNR. American journal of neuroradiology
Volume32
Issue9
Pagination1662-8
Date Published2011 Oct
Abstract

There is a well-known relationship between MS and damage to the optic nerve, but advanced, quantitative MR imaging methods have not been applied to large cohorts. Our objective was to determine whether a short imaging protocol (< 10 minutes), implemented with standard hardware, could detect abnormal water diffusion in the optic nerves of patients with MS.

DOI10.1007/s12975-011-0110-4
Alternate JournalAJNR Am J Neuroradiol