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Diffusion tensor imaging in children with periventricular leukomalacia: variability of injuries to white matter tracts.
|Title||Diffusion tensor imaging in children with periventricular leukomalacia: variability of injuries to white matter tracts.|
|Publication Type||Journal Article|
|Year of Publication||2007|
|Authors||Nagae LM, Hoon AH, Stashinko E, Lin D, Zhang W, Levey E, Wakana S, Jiang H, Leite CC, Lucato LT, van Zijl PCM, Johnston MV, Mori S|
|Journal||AJNR. American journal of neuroradiology|
|Date Published||2007 Aug|
Conventional MR imaging shows evidence of brain injury and/or maldevelopment in 70%-90% of children with cerebral palsy (CP), though its capability to identify specific white matter tract injury is limited. The great variability of white matter lesions in CP already demonstrated by postmortem studies is thought to be one of the reasons why response to treatment is so variable. Our hypothesis is that diffusion tensor imaging (DTI) is a suitable technique to provide in vivo characterization of specific white matter tract lesions in children with CP associated with periventricular leukomalacia (PVL).
|Alternate Journal||AJNR Am J Neuroradiol|