Copper(I)-catalyzed synthesis of 5-arylindazolo[3,2-b]quinazolin-7(5H)-one via Ullmann-type reaction.

TitleCopper(I)-catalyzed synthesis of 5-arylindazolo[3,2-b]quinazolin-7(5H)-one via Ullmann-type reaction.
Publication TypeJournal Article
Year of Publication2013
AuthorsChen D-S, Dou G-L, Li Y-L, Liu Y, Wang X-S
JournalThe Journal of organic chemistry
Volume78
Issue11
Pagination5700-4
Date Published2013 Jun 7
Abstract

The treatment of 2-amino-N'-arylbenzohydrazide and o-halogenated benzaldehyde in the presence of CuBr and Cs2CO3 gave 5-arylindazolo[3,2-b]quinazolin-7(5H)-one in high yields. This procedure contains an Ullmann-type reaction and provides an efficient method to construct fused tetracyclic heterocycles.

DOI10.1111/iju.12192
Alternate JournalJ. Org. Chem.