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Copper-catalyzed annulation of amidines for quinazoline synthesis.
|Title||Copper-catalyzed annulation of amidines for quinazoline synthesis.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Lv Y, Li Y, Xiong T, Pu W, Zhang H, Sun K, Liu Q, Zhang Q|
|Journal||Chemical communications (Cambridge, England)|
|Date Published||2013 Jul 21|
An efficient Cu-catalyzed synthesis of quinazolines via the C-N bond formation reactions between N-H bonds of amidines and C(sp(3))-H bonds adjacent to sulfur or nitrogen atoms in the commonly used solvents, such as DMSO, DMF, DMA, NMP or TMEDA, followed by intramolecular C-C bond formation reactions was developed for the first time.
|Alternate Journal||Chem. Commun. (Camb.)|