Constituents of the anti-asthma herbal formula ASHMI(TM) synergistically inhibit IL-4 and IL-5 secretion by murine Th2 memory cells, and eotaxin by human lung fibroblasts in vitro.

TitleConstituents of the anti-asthma herbal formula ASHMI(TM) synergistically inhibit IL-4 and IL-5 secretion by murine Th2 memory cells, and eotaxin by human lung fibroblasts in vitro.
Publication TypeJournal Article
Year of Publication2013
AuthorsJayaprakasam B, Yang N, Wen M-C, Wang R, Goldfarb J, Sampson H, Li X-M
JournalJournal of integrative medicine
Volume11
Issue3
Pagination195-205
Date Published2013 May
Abstract

Anti-asthma herbal medicine intervention (ASHMI(TM)), a combination of three traditional Chinese medicinal herbs developed in our laboratory, has demonstrated efficacy in both mouse models of allergic asthma, and a double-blind placebo-controlled clinical trial in patients with asthma. This study was designed to determine if the anti-inflammatory effects of individual herbal constituents of ASHMI(TM) exhibited synergy.

DOI10.1016/j.outlook.2013.03.006
Alternate JournalJ Integr Med