Comprehensive Analysis of Oncogenic Mutations in Lung Squamous Cell Carcinoma with Minor Glandular Component.

TitleComprehensive Analysis of Oncogenic Mutations in Lung Squamous Cell Carcinoma with Minor Glandular Component.
Publication TypeJournal Article
Year of Publication2013
AuthorsPan Y, Wang R, Ye T, Li C, Hu H, Yu Y, Zhang Y, Wang L, Luo X, Li H, Li Y, Shen L, Sun Y, Chen H
JournalChest
Date Published2013 Oct 24
Abstract

The mutations in oncogenic genes, such as EGFR, ALK, BRAF, HER2, DDR2, RET and AKT1, defined subsets of non-small cell lung cancers (NSCLC) with potential sensitivity to targeted therapies. At present, the mutational spectrum, prevalence and clinicopathologic characteristics in squamous cell carcinomas with minor (<10%) glandular component (SQCC-mGC) are not well established.

DOI10.1152/ajplung.00423.2012
Alternate JournalChest