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Combined transfection of Bcl-2 siRNA and miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells.
|Title||Combined transfection of Bcl-2 siRNA and miR-15a oligonucleotides enhanced methotrexate-induced apoptosis in Raji cells.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Ding L, Hu X-M, Wu H, Liu G-X, Gao Y-J, He D-M, Zhang Y|
|Journal||Cancer biology & medicine|
|Date Published||2013 Mar|
B-cell lymphoma 2 (Bcl-2) is an important member of the Bcl-2 family of proteins that regulate the induction of apoptosis. This study aims to investigate whether Bcl-2 small interfering RNA (siRNA) combined with miR-15a oligonucleotides (ODN) could enhance methotrexate (MTX)-induced apoptosis in Raji cells.
|Alternate Journal||Cancer Biol Med|