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Chemoselective oxidative C(CO)-C(methyl) bond cleavage of methyl ketones to aldehydes catalyzed by CuI with molecular oxygen.
|Title||Chemoselective oxidative C(CO)-C(methyl) bond cleavage of methyl ketones to aldehydes catalyzed by CuI with molecular oxygen.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Zhang L, Bi X, Guan X, Li X, Liu Q, Barry B-D, Liao P|
|Journal||Angewandte Chemie (International ed. in English)|
|Date Published||2013 Oct 18|
Aldehyde Termination: A novel copper-catalyzed transformation from methyl ketones into aldehydes has been accomplished. This method is applicable to a wide range of aromatic and aliphatic methyl ketones and chemoselectively produces aldehydes, accompanied by the release of hydrogen (H2 ) and carbon dioxide (CO2 ) as by-products.
|Alternate Journal||Angew. Chem. Int. Ed. Engl.|