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Chemoprevention of head and neck cancer by simultaneous blocking of epidermal growth factor receptor and cyclooxygenase-2 signaling pathways: preclinical and clinical studies.
|Title||Chemoprevention of head and neck cancer by simultaneous blocking of epidermal growth factor receptor and cyclooxygenase-2 signaling pathways: preclinical and clinical studies.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Shin DM, Zhang H, Saba NF, Chen AY, Nannapaneni S, Amin RARM, Müller S, Lewis M, Sica G, Kono S, Brandes JC, Grist WJ, Moreno-Williams R, Beitler JJ, Thomas SM, Chen Z, Shin HJC, Grandis JR, Khuri FR, Chen ZG|
|Journal||Clinical cancer research : an official journal of the American Association for Cancer Research|
|Date Published||2013 Mar 1|
We investigated the efficacy and underlying molecular mechanism of a novel chemopreventive strategy combining EGF receptor (EGFR) tyrosine kinase inhibitor (TKI) with cyclooxygenase-2 inhibitor (COX-2I).
|Alternate Journal||Clin. Cancer Res.|