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Bioactive limonoid and triterpenoid constituents of Turraea pubescens.
|Title||Bioactive limonoid and triterpenoid constituents of Turraea pubescens.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Yuan C-M, Tang G-H, Zhang Y, Wang X-Y, Cao M-M, Guo F, Li Y, Di Y-T, Li S-L, Hua H-M, He H-P, Hao X-J|
|Journal||Journal of natural products|
|Date Published||2013 Jun 28|
Eleven new limonoids, turrapubins A-K (1-11), and three new triterpenoids (12-14), along with 14 known compounds, were isolated from the twigs of Turraea pubescens. The structures of 1-14 were elucidated on the basis of NMR and MS analysis. Compounds 12, 16, 18, and 19 exhibited inhibitory activities against lipopolysaccharide-induced nitric oxide production in RAW264.7 cells. In addition, compounds 2, 11, 18, and 26 exhibited inhibitory activities against brine shrimp larvae (Artemia salina) at 100 ppm with the corrected mortality ranging from 81.7% to 100%.
|Alternate Journal||J. Nat. Prod.|