Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.

TitleBenzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.
Publication TypeJournal Article
Year of Publication2013
AuthorsCai H-Y, Wang T, Zhao J-C, Sun P, Yan G-R, Ding H-P, Li Y-X, Wang H-Y, Zhu W-L, Chen K-X
JournalActa pharmacologica Sinica
Volume34
Issue11
Pagination1397-402
Date Published2013 Nov
Abstract

Fatty acid-binding protein 4 (FABP4) plays an important role in maintaining glucose and lipid homeostasis. The aim of this study was to find new inhibitors of FABP4 for the treatment of type 2 diabetes.

DOI10.4103/2229-516X.117051
Alternate JournalActa Pharmacol. Sin.