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Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.
|Title||Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Cai H-Y, Wang T, Zhao J-C, Sun P, Yan G-R, Ding H-P, Li Y-X, Wang H-Y, Zhu W-L, Chen K-X|
|Journal||Acta pharmacologica Sinica|
|Date Published||2013 Nov|
Fatty acid-binding protein 4 (FABP4) plays an important role in maintaining glucose and lipid homeostasis. The aim of this study was to find new inhibitors of FABP4 for the treatment of type 2 diabetes.
|Alternate Journal||Acta Pharmacol. Sin.|