Benazepril inhibited the NF-κB and TGF-β networking on LV hypertrophy in rats.

TitleBenazepril inhibited the NF-κB and TGF-β networking on LV hypertrophy in rats.
Publication TypeJournal Article
Year of Publication2013
AuthorsYan S-H, Zhao N-W, Zhu X-X, Wang Q, Wang H-D, Fu R, Sun Y, Li Q-Y
JournalImmunology letters
Volume152
Issue2
Pagination126-34
Date Published2013 May
Abstract

Benazepril, an angiotensin-converting enzyme (ACE) inhibitor, has been used to treat hypertension, congestive heart failure, and chronic renal failure. However, its biological activity and mechanism of action in inflammation are not fully identified. The present study was designed to determine the in vivo anti-inflammatory effects of benazepril on LV hypertrophy in rats.

DOI10.1371/journal.pone.0065042
Alternate JournalImmunol. Lett.