Bead capture increases the sensitivity of sputum microscopy for the diagnosis of tuberculosis in Beijing, China.

TitleBead capture increases the sensitivity of sputum microscopy for the diagnosis of tuberculosis in Beijing, China.
Publication TypeJournal Article
Year of Publication2013
AuthorsWang X, Zhao L, Yu X, Li Y, Ma Y, Dong L, Huang H
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume107
Issue11
Pagination741-3
Date Published2013 Nov
Abstract

A review of the scientific literature concluded that indirect smear can improve detection of TB in sputum compared to direct smear. However few laboratories have access to centrifugation in order to perform indirect smear. This study investigated whether an alternative method of magnetic bead concentration could enhance diagnosis of TB in China in laboratories which only perform direct smear microscopy.

DOI10.1093/trstmh/trt068
Alternate JournalTrans. R. Soc. Trop. Med. Hyg.