Basolateral amygdala lesion inhibits the development of pain chronicity in neuropathic pain rats.

TitleBasolateral amygdala lesion inhibits the development of pain chronicity in neuropathic pain rats.
Publication TypeJournal Article
Year of Publication2013
AuthorsLi Z, Wang J, Chen L, Zhang M, Wan Y
JournalPloS one
Volume8
Issue8
Paginatione70921
Date Published2013
Abstract

Chronicity of pain is one of the most interesting questions in chronic pain study. Clinical and experimental data suggest that supraspinal areas responsible for negative emotions such as depression and anxiety contribute to the chronicity of pain. The amygdala is suspected to be a potential structure for the pain chronicity due to its critical role in processing negative emotions and pain information.

DOI10.1371/journal.pone.0071430
Alternate JournalPLoS ONE