Association between MDM2 SNP309 T>G and risk of gastric cancer: a meta-analysis.

TitleAssociation between MDM2 SNP309 T>G and risk of gastric cancer: a meta-analysis.
Publication TypeJournal Article
Year of Publication2013
AuthorsTian X, Tian Y, Ma P, Sui C-G, Meng F-D, Li Y, Fu L-Y, Jiang T, Wang Y, Ji F-J, Fang X-D, Jiang Y-H
JournalAsian Pacific journal of cancer prevention : APJCP
Volume14
Issue3
Pagination1925-9
Date Published2013
Abstract

As a negative regulator of P53, MDM2 plays an important role in carcinogenesis; a polymorphism in its promoter region. SNP309 T>G, is known to increase the expression of MDM2, thus being considered related to higher susceptibility to neoplasia. However, no agreement has been achieved regarding its effects on gastric cancer.

DOI10.1002/asia.201300578
Alternate JournalAsian Pac. J. Cancer Prev.