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Association between MDM2 SNP309 T>G and risk of gastric cancer: a meta-analysis.
|Title||Association between MDM2 SNP309 T>G and risk of gastric cancer: a meta-analysis.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Tian X, Tian Y, Ma P, Sui C-G, Meng F-D, Li Y, Fu L-Y, Jiang T, Wang Y, Ji F-J, Fang X-D, Jiang Y-H|
|Journal||Asian Pacific journal of cancer prevention : APJCP|
As a negative regulator of P53, MDM2 plays an important role in carcinogenesis; a polymorphism in its promoter region. SNP309 T>G, is known to increase the expression of MDM2, thus being considered related to higher susceptibility to neoplasia. However, no agreement has been achieved regarding its effects on gastric cancer.
|Alternate Journal||Asian Pac. J. Cancer Prev.|