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Assessment of MRI parameters as imaging biomarkers for radiation necrosis in the rat brain.
|Title||Assessment of MRI parameters as imaging biomarkers for radiation necrosis in the rat brain.|
|Publication Type||Journal Article|
|Year of Publication||2012|
|Authors||Wang S, Tryggestad E, Zhou T, Armour M, Wen Z, Fu D-X, Ford E, van Zijl PCM, Zhou J|
|Journal||International journal of radiation oncology, biology, physics|
|Date Published||2012 Jul 1|
Radiation necrosis is a major complication of radiation therapy. We explore the features of radiation-induced brain necrosis in the rat, using multiple MRI approaches, including T(1), T(2), apparent diffusion constant (ADC), cerebral blood flow (CBF), magnetization transfer ratio (MTR), and amide proton transfer (APT) of endogenous mobile proteins and peptides.
|Alternate Journal||Int. J. Radiat. Oncol. Biol. Phys.|